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Mary&May Spicule Retinol PDRN Cream 15g
MARY&MAY

Mary&May Spicule Retinol PDRN Cream 15g

★★★★★4.7 · 14 reviews
AED 56.80AED 71.00

In stock — ships within 24h

Targets these concerns
Anti AgingDullnessFine LinesLarge PoresUneven ToneWrinkles
1
100% authentic, sourced from Korea
Free UAE shipping
Personally tested
14-day returns
Description

Mary&May Spicule Retinol PDRN Cream is a powerful yet gentle Korean anti-aging cream that combines three generations of skincare innovation in one jar — marine-derived micro-spicules, nano liposome retinol, and soothing PDRN. It's designed to target wrinkles, pores, and uneven texture while keeping skin calm and comfortable.

The natural marine-derived micro-spicules are 1/40 the size of your pores, acting like invisible micro-channels to deliver actives deeper into skin. Nano liposome retinol is stabilized for enhanced penetration and reduced irritation, smoothing fine lines and refining skin texture over time. What makes this cream truly special is the CICA PDRN complex — salmon-derived PDRN (Sodium DNA) paired with centella-inspired soothing ingredients — which promotes recovery and keeps skin calm throughout the retinol journey. Panthenol, ceramide NP, and shea butter round out a rich yet fast-absorbing formula.

Why customers love it

  • Marine micro-spicules — 1/40 the size of pores for deeper active delivery
  • Nano liposome retinol — stabilized retinol for wrinkles, pores, and texture
  • CICA PDRN complex — soothes and promotes skin recovery
  • Panthenol + Ceramide NP — strengthen and repair the moisture barrier
  • Niacinamide — brightens and evens out skin tone
  • Nourishing base — shea butter, macadamia seed oil, and polyglutamic acid

Perfect for: fine lines, wrinkles, enlarged pores, uneven texture, dullness, anyone looking for a retinol that's both effective and gentle, skincare lovers who want spa-grade results at home.

Key ingredients

Full INCI list is printed on the carton. Formulated without parabens, sulfates or artificial dyes. Patch-test before first use.

Shipping & returns

Free shipping across the UAE, delivered within 1–3 business days. Unopened items can be returned within 14 days for a full refund.

How to use
1Apply to clean, dry skin.
2Use a pea-sized amount, morning and/or night.
3Pat gently until fully absorbed.
4Always follow with SPF in the morning.

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Reviews

4.7
★★★★★
14 reviews
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10
4
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RS
RSVerified
★★★★★
17 Apr 2026

Lovely productOnly been using it a couple weeks but I can already see a difference

UZ
Uzma ShahzadiVerified
★★★★★
8 Apr 2026

very nice

CH
Chelsea weaverVerified
★★★★★
7 Apr 2026

Will always be one of my go to for my face is works and I can honestly say within a month I've noticed a change and fewer break outs.

AN
anyone
★★★★★
5 Apr 2026

i have to say that i definitely put off trying this item for a long time, because of an irrational fear of the word spicule. i had no clue what that meant. spikes? nano spikes? nano spike cream on my face?i got past my fear last night without looking it up. like other retinol creams, this comes out as a small yellow line of cream. not much is needed. and then what?i went to bed. i'm happy to say that the next day, as i'm writing this, my face is not a den of hives. it wasn't really angry or broken out. it looked pretty calm. actually happy. this is a huge deal. i had no idea whether a previously unknown-to-me K-beauty product could potentially work or harm me.upong writing this review, i quickly looked up spicule. as an NBC article puts it, spicules aren't actually spikes, but rather more like microneedles. did it hurt? no.what follows is quoted from the NBC article.The main benefit of adding skin care with spicules into your routine is that it can help other active ingredients penetrate better. “They can also improve texture, refine pores and make your treatments more effective without harsh scrubbing,” says Dr. Hannah Kopelman, a board-certified dermatologist in New York. “And unlike using a rough scrub to exfoliate, spicules are uniform, so they reduce the risk of irritation.”The experts I spoke to also said that one of the major benefits of spicules is that they mimic the effects of in-office treatments — like microneedling — without you having to spend the time going into an office or spend the money.that sounds great. so would it work for me? theoretically. seems to. no breakouts for my sensitive skin. that's also good. the NBC article further stated that broken skin (an active eczema or rosacea breakout, etc) is contraindicated for use of this item. and yes, with retinol, skin can get sensitized, so there's that risk. don't stack aggressive exfoliation with retinol use. makes sense.and as you probably know, some retinol products are stronger and harsher than others. these products contain retinols, retinals, retinoids, and so on. read up elsewhere on the science and medicine behind that. there's a whole range, let's just say. let's also note that i've seen the best results with retinol products that have micro-encapsulated retinol for slower release. are the spicules in this product along those lines? well, based on my guess and check method, this seems to work.so hopefully you'll find this useful. a little goes a long way, so this should last quite a while. it has some moisturizing benefits as well. no fragrance. not too yellow. since it's not the most expensive product -- the value for the money also holds up. 5 stars from me. hopefully for you, too.

SE
SesoVerified
★★★★★
27 Mar 2026

Amazing quality

LY
Lyra S.
★★★★★
22 Mar 2026

I've been using this cream for around a month now, so it's too early to tell whether it's going to improve these fine lines on my forehead, but man, my skin loves it! It's one of the few retinols I can use without getting super dry and peeling. I don't know if it's the combo of PDRN with the retinol, but my skin drinks it up and is super happy. I feel like overall my skin feels brighter and smoother. I'm really hoping it will take care of the lines, but they're pretty deep, so we'll see!The cream itself doesn't feel thick or sticky. It has no fragrance. It's just nice and absorbs great. I honestly have no complaints and will keep using this product. It's a stellar value for what it is, and just a little bit goes a long way! Great find!

MA
MarilinVerified
★★★★★
11 Mar 2026

Excelente está si es original lo recomiendo . Y si sierra los poros .

CA
Carol FalkenbergVerified
★★★★★
19 Feb 2026

Gives your overall look a glow

AM
Amazon Customer
★★★★★
18 Feb 2026

I’ve been using the Mary&May Spicule Retinol PDRN Cream for a while now, and it feels like a mini at-home skin booster treatment. The mix of micro-spicules, 0.1% nano-liposome retinol, and PDRN really makes this stand out from your average retinol cream.First off -- yes, it tingles. The 'spicule sting' is real. It’s kind of a prickly feeling when you first put it on, but it fades fairly quickly. I actually take that as a sign it’s doing its job, since the 2,000 ppm micro-spicules are designed to help the active ingredients absorb deeper. It’s not painful, just noticeable.As for texture, it’s a lightweight cream that sinks in fast and doesn’t feel greasy. I was worried about dryness since retinol can wreck my skin barrier, but this formula feels surprisingly gentle and balanced.The biggest change I’ve seen is around my nose and forehead. My pores look tighter, and my skin texture feels smoother -- especially the morning after. There’s definitely that 'post-facial glow effect' when I wake up.I’m giving it a solid 4.5 stars. It gives visible smoothing and pore-refining results, feels like an advanced at-home treatment, isn’t overly drying or harsh, plus it's affordable and great value especially for anyone who wants to try any of the three; spicule, retinol, and PDRN. If you want that glass-skin, just-left-the-clinic look without actually going to a clinic, this is a solid pick.

AM
Amazon Customer
★★★★☆
15 Feb 2026

This Korean face moisturizer is interesting because it uses marine spicules alongside nano liposome retinol, which isn't something I've come across in other K beauty products. When you first rub it onto your skin, you definitely feel a bit of tingling. It's not painful, but you can tell the ingredients are doing something. I like that they balanced this intense treatment with calming ingredients like ceramide and panthenol, which kept my sensitive skin from reacting badly. It's designed to help with pore texture and firmness, and after steady nighttime use, my skin looks smoother to me. The container is pretty small (0.5 oz), so you really have to watch how much you use each time. Overall, I'd say this is a great product, but I wish there was more in the container for this price.

NI
Nicky N.
★★★★☆
14 Feb 2026

This cream is a blend of retinol with spicules and PDRN. it's a unique texture and a bit gritty because of the marine spicules, which took me some time to get used to. It does absorb nicely without feeling heavy or greasy. I like that the nano liposome retinol didn't cause any irritation on my sensitive skin. it contains soothing ceramides and panthenol. after using it, i did noticed a slight improvement in texture but not a dramatic transformed though. Its a decent moisturizer though. no scent or a subtle scent.

MI
Mimi
★★★★☆
14 Feb 2026

This cream feels really nice on my sensitive skin. The texture is light and sinks in quickly, so it doesn’t feel heavy. I get a bit of a tingling sensation, but it goes away fast and doesn’t bother me. I also appreciate that it has no scent because that usually works better for me.It leaves my skin looking smoother and more hydrated. A little truly goes a long way, so even the small tube lasts longer than I thought it would. The price feels fair considering the ingredients and how well it works.

ME
Meredith
★★★★☆
11 Feb 2026

Easy to apply and tingles for a moment or two after putting it on. Super quick absorption so it didn't slow down my skin care routine. Little to no scent and since my skin is sensitive, it didn't irritate it at all. I've been using it daily for almost a week and using it alongside a retinol cleanser. Skin is definitely softer and smoother. I can't say whether using it on its own does the trick, but with mature skin, you need to pull your whole skin care routine together and make it work for you. I felt that adding this moisturizer was a really positive addition. Would buy this again.

GÜLÇİN ÇELİKVerified
★★★★★
18 Jan 2026

Çok başarılı, cilde uygun bir nemlendirici ile birlikte kullanılmalı